Supplementary MaterialsDocument S1. causative mutations in these genes, specifically those that

Supplementary MaterialsDocument S1. causative mutations in these genes, specifically those that have been positionally mapped by genetic linkage studies. When hearing impairment occurs as part of a genetic syndrome, candidate genes can usually be identified on the basis of a hypothesized function consistent with the physiological effects of the syndrome or by the correlation of… Continue reading Supplementary MaterialsDocument S1. causative mutations in these genes, specifically those that

Myotonic dystrophy type 2 (DM2) is definitely a dominantly inherited autosomal

Myotonic dystrophy type 2 (DM2) is definitely a dominantly inherited autosomal disease with multi-systemic Rivaroxaban Diol medical features and it is caused by expansion of a CCTG tetranucleotide repeat in the 1st intron of the zinc finger protein 9 (ZNF9) gene in 3q21. at fluorescence and transmission electron microscopy by using a panel of antibodies… Continue reading Myotonic dystrophy type 2 (DM2) is definitely a dominantly inherited autosomal