Innate immune system receptors NOD1 and NOD2 are turned on by bacterial peptidoglycans resulting in recruitment of adaptor kinase RIP2, which, upon phosphorylation and ubiquitination, turns into a scaffold for downstream effectors. energetic state is certainly a well balanced dimer whilst the inactive kinase is within a monomer-dimer equilibrium, in keeping with the noticed structural… Continue reading Innate immune system receptors NOD1 and NOD2 are turned on by