Supplementary MaterialsFigure 5source data 1: Complete tandem mass tagging mass spectrometry data. have used misfolded prion protein (PrP*) as a model to investigate how mammalian cells recognize and degrade misfolded GPI-anchored proteins. While most misfolded membrane proteins are degraded by proteasomes, misfolded GPI-anchored proteins are degraded in lysosomes primarily. Quantitative movement cytometry analysis demonstrated that… Continue reading Supplementary MaterialsFigure 5source data 1: Complete tandem mass tagging mass spectrometry data