Category : Atrial Natriuretic Peptide Receptors

Supplementary MaterialsSupplementary Desk 1

Supplementary MaterialsSupplementary Desk 1. the FAK/PI3K/Akt signaling pathway. Conclusion: RHPN1-AS1-miR-596-LETM1 axis plays a crucial role in EOC progression. Our findings may provide encouraging drug targets for EOC treatment. Methods: We decided the aberrantly expressed lncRNAs in EOC via microarray analysis and validated RHPN1-AS1 expression by qRT-PCR. The RHPN1-AS1-miR-596-LETM1 axis was examined by dual-luciferase reporter assay and RIP assay. The mechanism of RHPN1-AS1 was investigated through gain- and loss-of-function studies both in vivo and in vitro. Inhibits Cell Migration, Invasion and Proliferation in Head and Neck Squamous Cell Carcinoma. J Malignancy. 2019; 10:4000C08. 10.7150/jca.29029 [PMC free article] [PubMed] [CrossRef] [Google Scholar] 16. Ding L, Wang L, Li Z, Jiang X, Xu Y, Han N. The positive opinions loop of RHPN1-AS1/miR-1299/ETS1 accelerates the deterioration of gastric cancers. Biomed Pharmacother. 2020; 124:109848. 10.1016/j.biopha.2020.109848 [PubMed] [CrossRef] [Google Scholar] 17. Fen H, Hongmin Z, Wei W, Chao Y, Yang Y, Bei L, Zhihua S. RHPN1-AS1 Drives the Development of Hepatocellular Carcinoma via Regulating miR-596/IGF2BP2 Axis. Curr Pharm Des. 2020; 25:4630C40. 10.2174/1381612825666191105104549 [PubMed] [CrossRef] [Google Scholar] 18. Li X, Zhang X, Yang C, Cui S, Shen Q, Xu S. The lncRNA RHPN1-AS1 downregulation promotes gefitinib level of resistance by concentrating on miR-299-3p/TNFSF12 pathway in NSCLC. Cell Routine. 2018; 17:1772C83. 10.1080/15384101.2018.1496745 [PMC free article] [PubMed] [CrossRef] [Google Scholar] 19. Lu L, Yu X, Zhang L, Ding X, Skillet H, Wen X, Xu S, Xing Y, Enthusiast J, Ge S, Zhang H, Jia R, Enthusiast X. The Long Non-Coding RNA RHPN1-AS1 Stimulates Uveal Melanoma Development. Int J Mol Sci. 2017; 18:18. 10.3390/ijms18010226 [PMC free article] [PubMed] [CrossRef] [Google Scholar] 20. Liu SM, Lin CH, Lu J, Lin IY, Tsai MS, UK-427857 inhibitor database Chen MH, Ma N. miR-596 Modulates Melanoma Development by Regulating Cell Loss of life and Success. J Invest Dermatol. 2018; 138:911C21. 10.1016/j.jid.2017.11.016 [PubMed] [CrossRef] [Google Scholar] 21. Wang L, En H, Yang L, Zhang Y, Sunlight B, Gao J. miR-596 suppresses the appearance of Survivin and enhances the awareness of osteosarcoma cells towards the molecular concentrating on agent anlotinib. Onco Goals Ther. 2019; 12:6825C38. 10.2147/OTT.S215145 [PMC free article] [PubMed] [CrossRef] [Google Scholar] 22. Ma M, Yang J, Wang B, Zhao Z, Xi JJ. High-Throughput Id of miR-596 Inducing p53-Mediated Apoptosis in HeLa and HCT116 Cells Using Cell Microarray. SLAS Technol. 2017; 22:636C45. 10.1177/2472630317720870 [PubMed] [CrossRef] [Google Scholar] 23. Piao L, Feng Y, Yang Z, Qi W, Li H, Han H, Xuan Y. LETM1 is certainly a potential cancers stem-like cell marker and predicts poor prognosis in colorectal adenocarcinoma. Pathol Res Pract. 2019; 215:152437. 10.1016/j.prp.2019.152437 [PubMed] [CrossRef] [Google Scholar] 24. Yang Z, Ni W, Cui C, Qi W, Piao L, Xuan Y. Id of LETM1 being a marker of cancers stem-like cells and predictor of poor prognosis in esophageal squamous cell carcinoma. Hum Pathol. 2018; 81:148C56. 10.1016/j.humpath.2018.07.001 [PubMed] [CrossRef] [Google Scholar] 25. Li N, Zheng Y, Xuan C, Lin Z, Piao L, Liu S. LETM1 overexpression is certainly correlated with the scientific features and success outcome of breasts cancers. Int J Clin Exp Pathol. 2015; 8:12893C900. [PMC free of charge content] [PubMed] [Google Scholar] 26. Piao L, Yang Z, Feng Y, Zhang C, Cui C, Xuan Y. LETM1 is certainly a potential biomarker of prognosis in lung non-small cell carcinoma. BMC Cancers. 2019; 19:898. 10.1186/s12885-019-6128-9 [PMC free of charge article] [PubMed] [CrossRef] [Google Scholar] 27. Li H, Piao L, Xu D, Xuan Y. LETM1 is certainly a potential biomarker that predicts poor prognosis in gastric adenocarcinoma. Exp Mol Pathol. 2020; 112:104333. 10.1016/j.yexmp.2019.104333 [PubMed] [CrossRef] [Google Scholar] 28. Huang B, Zhang J, Zhang X, Huang C, Hu G, Li S, Xie T, Liu M, Xu UK-427857 inhibitor database Y. Suppression of UK-427857 inhibitor database LETM1 by siRNA inhibits cell invasion and proliferation of bladder cancers cells. Oncol Rep. 2017; 38:2935C40. 10.3892/or.2017.5959 [PubMed] [CrossRef] [Google Scholar] 29. Martens-Uzunova Ha sido, B?ttcher UK-427857 inhibitor database R, Croce CM, Jenster UK-427857 inhibitor database G, Visakorpi T, Calin GA. Long noncoding RNA in prostate, bladder, and kidney cancers. Eur Urol. 2014; 65:1140C51. 10.1016/j.eururo.2013.12.003 [PubMed] [CrossRef] [Google Scholar] 30. Mmp13 Linder B, Grozhik AV, Olarerin-George AO, Meydan C, Mason.