The annals of specific therapy for hereditary tumors goes back to middle 1980s and involves several reports demonstrating regression of familial colon polyps upon administration of sulindac. and sporadic medullary thyroid tumor. Vismodegib, an inhibitor of SMO oncoprotein, triggered regression of basal-cell carcinomas in individuals with Gorlin symptoms. Down-regulation of mTOR kinase by everolimus continues… Continue reading The annals of specific therapy for hereditary tumors goes back to