Fusion of the androgen receptor-regulated (AR-regulated) gene with in prostate cancer (PCa) causes androgen-stimulated overexpression of ERG, an ETS transcription factor, but critical downstream effectors of ERG-mediating PCa development remain to be established. stimulated, and identify SOX9 as a critical downstream effector of ERG in fusionCpositive PCa. Introduction The androgen receptor (AR) plays a central… Continue reading Fusion of the androgen receptor-regulated (AR-regulated) gene with in prostate cancer
Tag: Rabbit polyclonal to AP4E1.
Great efforts have already been made to develop novel and efficacious
Great efforts have already been made to develop novel and efficacious therapeutics against pancreatic cancer to improve the treatment outcomes. decreased c-FLIP levels in every tested cell line and survivin levels in some of the tested cell lines. Enforced expression of ectopic c-FLIP but not survivin abolished the cooperative induction of apoptosis by the combination… Continue reading Great efforts have already been made to develop novel and efficacious