Fusion of the androgen receptor-regulated (AR-regulated) gene with in prostate cancer (PCa) causes androgen-stimulated overexpression of ERG, an ETS transcription factor, but critical downstream effectors of ERG-mediating PCa development remain to be established. stimulated, and identify SOX9 as a critical downstream effector of ERG in fusionCpositive PCa. Introduction The androgen receptor (AR) plays a central… Continue reading Fusion of the androgen receptor-regulated (AR-regulated) gene with in prostate cancer