In individuals with acute promyelocytic leukemia (APL), ~98% express the promyelocytic leukemia (PML)-retinoic acid receptor (RAR) fusion protein. transfected NLS-RAR in NB4 cells, puromycin was used to select the stable transfected cell lines. Cell Counting Kit-8 and circulation cytometry analysis revealed the efficient overexpression of NLS-RAR significantly advertised NB4 cell proliferation and inhibited all-trans retinoic… Continue reading In individuals with acute promyelocytic leukemia (APL), ~98% express the promyelocytic