Vancoresmycin is a book tetramic acid antibiotic probably interfering with functions of the cytoplasmic membrane. (C1744T) in spr0813 leading to the formation of a XMD8-92 truncated permease lacking 2 of the 10 predicted transmembrane helices. As exhibited by deletion and transformation analysis and reconstructing the spr0813C1744T mutation in the wild-type background this nucleotide exchange was… Continue reading Vancoresmycin is a book tetramic acid antibiotic probably interfering with functions