Proline oxidase (POX) catalytically changes proline to pyrroline-5-carboxylate. triggered as a mobile protective response towards the toxic ramifications of gp120. An operating and direct part of POX in gp120-mediated neuronal autophagy was examined by inhibition and overexpression research. Inhibition of POX activity with a competitive inhibitor dehydroproline reduced ROS amounts concomitant with minimal neuronal autophagy.… Continue reading Proline oxidase (POX) catalytically changes proline to pyrroline-5-carboxylate. triggered as a