Supplementary MaterialsData_Sheet_1. from neuroblastoma patients and recognize a repeated anaplastic lymphoma kinase mutation (R1275Q) leading to two high affinity neoepitopes when portrayed in complicated with common HLA alleles. Evaluation from the X-ray buildings of both peptides destined to HLA-B*15:01 uncovers significantly different conformations with measurable adjustments in the balance of the proteins complexes, as the… Continue reading Supplementary MaterialsData_Sheet_1. from neuroblastoma patients and recognize a repeated anaplastic lymphoma