Double-stranded RNA is normally a common pathogen-associated molecular pattern that is

Double-stranded RNA is normally a common pathogen-associated molecular pattern that is recognized by cellular Toll-like receptor 3 (TLR3) and used by virus-infected cells to activate specific transcription factors and trigger induction of antiviral genes. bound to TLR3 after dsRNA-stimulation of cells. The response was biphasic: upon dsRNA-treatment we observed an immediate increase in cell motility… Continue reading Double-stranded RNA is normally a common pathogen-associated molecular pattern that is