Compact disc4+ regulatory T cells (Tregs) expressing the transcription factor forkhead box P3 (FoxP3) play an important part in self-tolerance and immune homeostasis. malignancy. The recent success of immune checkpoint inhibitors (ICIs) that target immune checkpoint molecules indicated by Tregs or effector T cells indicates, that meddling with meddlers represents an effective strategy in malignancy… Continue reading Compact disc4+ regulatory T cells (Tregs) expressing the transcription factor forkhead