Complement activation plays a major role in several renal pathophysiological conditions. uremic syndrome (aHUS) is usually a thrombotic microangiopathy characterized by excessive match activation on the surface of the microcirculation. It is a severe rare disease which leads to end-stage renal failure (ESRF) and/or to death in more than 50% of patients without treatment. In… Continue reading Complement activation plays a major role in several renal pathophysiological conditions.