Mutations in the retinal pigment epithelium (RPE) gene RPE65 are associated with multiple blinding diseases including Lebers Congenital Amaurosis (LCA). 44% of WT for naked DNA). No reduction in expression at the message MK-0822 novel inhibtior level was observed from PI-6 month data. Spectral electroretinography (ERG) demonstrated significant improvement in cone ERG amplitudes in treated… Continue reading Mutations in the retinal pigment epithelium (RPE) gene RPE65 are associated