DNAX-activating protein of 12 kD (DAP12) is an immunoreceptor tyrosine-based activation

DNAX-activating protein of 12 kD (DAP12) is an immunoreceptor tyrosine-based activation motif (ITAM)-containing adaptor protein within myeloid cells and organic killer cells and it couples to several receptors that mediate either mobile activation or inhibition. phosphotyrosine-binding domains. In response to LPS DOK3 was phosphorylated within a DAP12- and Src-dependent way which resulted in translocation of… Continue reading DNAX-activating protein of 12 kD (DAP12) is an immunoreceptor tyrosine-based activation