Objective The anti-apoptotic action of HBEGF and its own regulation by Objective The anti-apoptotic action of HBEGF and its own regulation by

Expression and signaling of CD30 a tumor necrosis factor (TNF) receptor family member is upregulated in numerous lymphoid-derived neoplasias most notably anaplastic large cell lymphoma (ALCL) and Hodgkin’s lymphoma (HL). was potentiated resulting in augmented expression of these NF-κB-responsive genes. These findings indicate that ARNT functions in concert with RelB in a CD30-induced negative feedback… Continue reading Objective The anti-apoptotic action of HBEGF and its own regulation by Objective The anti-apoptotic action of HBEGF and its own regulation by