Intravenously administered bacteria apparently accumulate in tumors. Antitumor activity was achieved without significant toxicity and was associated with infiltration of inflammatory cells and dependent on the LIGHT receptors herpes simplex virus entrance mediator (HVEM) and lymphotoxin-β receptor (LTβR). These results provide proof that nonvirulent bacterias could be exploited as concentrating on vehicles for regional generation… Continue reading Intravenously administered bacteria apparently accumulate in tumors. Antitumor activity was achieved