The connexin 43 (Cx43) hemichannel (HC) in the mechanosensory osteocytes is a major portal for the release of factors responsible for the anabolic effects of mechanical loading on bone formation and remodeling. of the HC. These results determine an unconventional function of integrin that functions as a mechanical tether to induce opening of the HC… Continue reading The connexin 43 (Cx43) hemichannel (HC) in the mechanosensory osteocytes is