Current methods of analyzing sperm chromatin competency overlook the inner sperm compartment which is inaccessible to probes and reagents. ROC calculated cut-off was >70.0% for normal toroid integrity (sensitivity 0.98, buy 315183-21-2 specificity 0.33, and diagnostic accuracy 78.3%). An association between normal sperm toroid integrity and miscarriage was evident when the staining treatment included acidified… Continue reading Current methods of analyzing sperm chromatin competency overlook the inner sperm