Etoposide, a trusted anticancer drug, displays low and variable dental bioavailability

Etoposide, a trusted anticancer drug, displays low and variable dental bioavailability due to the fact to be substrate for the efflux transporter, P-glycoprotein (P-gp). (p 0.001) in the current presence of verapamil (100 g/mL) and TPGS (on the concentration selection of 0.002- 0.1 mg/mL), suggesting the inhibition of P-gp situated in the intestine could be… Continue reading Etoposide, a trusted anticancer drug, displays low and variable dental bioavailability